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. 2016 Jul 15;30(14):1636–1644. doi: 10.1101/gad.281972.116

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© 2016 Zhang et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 2. — Lipid metabolic genes are up-regulated in HNF6 knockout livers. (A) Heat map and gene ontology (GO) analysis of differentially regulated genes in the HNF6 knockout. (B) The number of HNF6-binding sites near up-regulated genes and down-regulated genes. (C) The relative mRNA expression level of lipid metabolic genes known to be Rev-erbα and HDAC3 targets in the control and HNF6 knockout (KO) mice (Zhang et al. 2015). Data are expressed as mean ± SEM. (*) P < 0.05, Student's t-test. n = 4 per group.