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. Author manuscript; available in PMC: 2016 Nov 15.
Published in final edited form as: Life Sci. 2015 Oct 6;141:170–178. doi: 10.1016/j.lfs.2015.09.022

Figure 6.

Figure 6

Bendavia suppresses cardiac fibrosis by regulating gene expression of MMP9 and TIMP1. Real time PCR analysis for genes of (A) MMP9 in border zone, (B) TIMP1 in border zone, (C) MMP9 in remote area and (D) TIMP1 in remote area, at 6 weeks after myocardial infarction. All real time PCR data were normalized to β-actin and presented relative to the sham group. * p<0.05 vs. sham, # p<0.05 vs. MI/BZ (N=7 in each group). (E) Collagen deposition in border zone assessed by Picrosirius red staining. * p<0.05 vs. MI/BZ (N=26 in MI/BZ group, N=28 in MI/BZ+Bendavia group). (F) Collagen deposition in remote area assessed by Picrosirius red staining. (N=26 in MI/R group, N=28 in MI/R+Bendavia group).