Table 3.
Slopes for the lung parameters displayed by age and exposure
Slopes
(mean ± SEM) |
|||||
---|---|---|---|---|---|
11 weeks | 39 weeks | 67 weeks | 96 weeks | ||
Raw/lnMch | Room Air | 0.602±0.092* | 0.392±0.168* | 0.285±0.130*^ | 0.192 ± 0.130^ |
Carbon Black | 0.539±0.092* | 0.619±0.145* | 0.641±0.118*# | 0.243±0.118*^ | |
H/lnMch | Room Air | 15.499±1.993* | 7.755±3.638*^ | 5.019±2.818^ | 1.606±2.818^ |
Carbon Black | 14.789±1.993* | 7.502±3.151* | 9.125±2.573* | 2.617±2.573^ | |
G/lnMch | Room Air | 6.002±0.801* | 1.920±1.462^ | 1.843±1.133^ | 1.206±1.133^ |
Carbon Black | 4.017±0.801* | 3.547±1.266* | 5.663±1.034*# | 0.943±1.034^ | |
R/lnMch | Room Air | 1.378±0.138* | 0.581±0.252*^ | 0.524±0.195*^ | 0.268±0.195^ |
Carbon Black | 0.934±0.138*# | 0.854±0.218* | 0.870±0.178* | 0.283±0.178^ | |
E/lnMch | Room Air | 17.848±2.959* | 13.310±5.402* | 5.884±4.184^ | 4.369±4.184^ |
Carbon Black | 19.773±2.959* | 13.547±4.678* | 18.138±3.820*# | 7.134±3.820^ |
Slope significantly different from 0 (p < 0.05)
Significant difference from 11 weeks within exposure (p < 0.05)
Significant difference for CB compared to RA within age (p < 0.05)