Figure 4.

Patient group separation based on the cytokine network. (a) Unsupervised PCA of EoE-New/Active, EoE-Remission and Controls based on multiplex cytokine analysis from 72 h culture of esophageal biopsies. Two-dimensional PCA mapping represented 83% of variance (PC1=76% and PC2=7%). Each number represents a patient and patient groups are color-coded. (b) Unsupervised cluster analysis using cytokine levels between patient groups. Individual squares represent the cytokine concentration for the given cytokine (column) in a patient (row), with orange indicating higher cytokine levels and yellow indicating lower cytokine levels.