Table 1. Interactome of exogenous Plk3 obtained from SILAC.
| Gene name | Protein | Ratio H/L |
|---|---|---|
| ACAD9 | Acyl-CoA dehydrogenase family member 9, mitochondrial | 17.8 |
| CDC73 | Parafibromin | 9.1314 |
| ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 7.5376 |
| IGF2BP2 | Insulin-like growth factor 2 mRNA-binding protein 2 | 5.4704 |
| PLK3 | Serine/threonine-protein kinase Plk3; Serine/threonine-protein kinase Plk | 4.125 |
| CASP8 | Caspase-8 | 3.7484 |
| FAF2 | FAS-associated factor 2 | 3.59579 |
| AURKA; AURKC | Aurora kinase A; Aurora kinase C | 3.4786 |
| SSBP1 | Single-stranded DNA-binding protein; Single-stranded DNA-binding protein, mitochondrial | 3.2498 |
| TRAF7 | E3 ubiquitin-protein ligase TRAF7 | 3.2126 |
| HUWE1 | E3 ubiquitin-protein ligase HUWE1 | 3.1139 |
With Flag-Plk3 co-immunoprecipitated proteins with a “normalized heavy/light ratio” (H/L) of > 3 were considered as high-confidence members of the Plk3 interactome; see Supplementary information, Table S1 for the original data of the complete mass spectrometric analysis.