Table 1. Identification of EZH2-interacting proteins with MS.

Protein name	Total spectrum count	Percentage sequence coverage
PRC2
Histone-lysine N-methyltransferase EZH2	81	50.30%
Polycomb protein SUZ12	113	58.50%
Polycomb protein EED	11	22.50%
Histone-binding protein RBBP4	9	15.40%
Metal-response element-binding transcription factor 2	1	4.96%
Cellular stress response
X-ray repair cross-complementing protein 5	27	27.90%
Heat shock protein 90-beta	14	22.50%
Heat shock cognate 70 protein	3	6.38%
DNA replication
DNA topoisomerase 1	23	18.60%
DNA replication licensing factor MCM5	2	4.05%
DNA replication licensing factor MCM3	2	4.60%
RNA processing
Isoform 2 of Nucleolar RNA helicase 2	14	11.20%
Nucleosome assembly protein 1-like 1	20	19.30%
Nucleolar protein 56	5	12.10%
Nucleolar protein 58	2	5.10%
Rbosomal RNA methyltransferase NOP2	11	12.30%
Nucleolin	12	16.60%