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. 2016 Aug 4;11:19. doi: 10.1186/s13013-016-0083-x

Table 5.

Sensitivity of differentiating known clinical groups

Treatment (observation versus bracing or surgery) Treatment (observation versus bracing)
Observation (n = 139) Bracing/Surgery (n = 88) Observation (n = 139) Bracing (n = 67)
Mean SD Mean SD P-value* ESa Mean SD Mean SD P-value* ESa
EQ-5D-5L 0.96 0.07 0.89 0.15 <0.001 0.66 EQ-5D-5L 0.96 0.07 0.89 0.14 <0.001 0.62
SRS-22r SRS-22r
Function/activity 4.93 0.20 4.53 0.55 <0.001 0.95 Function/activity 4.93 0.20 4.58 0.50 <0.001 0.92
Pain 4.79 0.29 4.48 0.56 <0.001 0.70 Pain 4.79 0.29 4.52 0.49 <0.001 0.66
Appearance 4.03 0.55 3.78 0.74 0.004 0.39 Appearance 4.03 0.55 3.68 0.68 <0.001 0.57
Mental Health 4.49 0.51 4.31 0.67 0.028 0.29 Mental Health 4.49 0.51 4.32 0.63 0.038 0.30
Satisfaction with management 0.25 1.02 2.37 2.01 <0.001 −1.33 Satisfaction with management 0.25 1.02 2.13 2.01 <0.001 −1.18
Total 4.56 0.28 4.25 0.52 <0.001 0.73 Total 4.56 0.28 4.25 0.48 <0.001 0.78
Treatment (Bracing versus Surgery) Duration of Bracing
Bracing (n = 67) Surgery (n = 21) <1 year (n = 34) ≥1 year (n = 20)
Mean SD Mean SD P-value* ESa Mean SD Mean SD P-value* ESa
EQ-5D-5L 0.89 0.14 0.86 0.18 0.372 0.21 EQ-5D-5L 0.82 0.15 0.91 0.14 0.023 −0.66
SRS-22r SRS-22r
Function/activity 4.58 0.50 4.38 0.69 0.156 0.33 Function/activity 4.40 0.52 4.58 0.51 0.226 −0.34
Pain 4.52 0.49 4.33 0.73 0.184 0.30 Pain 4.54 0.34 4.48 0.58 0.657 0.14
Appearance 3.68 0.68 4.11 0.83 0.021 −0.56 Appearance 3.60 0.74 3.67 0.62 0.732 −0.10
Mental Health 4.32 0.63 4.30 0.83 0.924 0.02 Mental Health 4.27 0.65 4.28 0.66 0.972 −0.01
Satisfaction with management 2.13 2.01 3.15 1.84 0.046 −0.53 Satisfaction with management 2.43 2.12 2.52 1.96 0.875 −0.04
Total 4.25 0.48 4.25 0.67 0.991 0.002 Total 4.19 0.49 4.22 0.50 0.780 −0.08
Cobb angle (mild or moderate versus severe) Modified Lenke Classification
≤40° (n = 205) >40° (n = 20) Thoracic curve (n = 86) Lumbar curve (n = 38) Thoracic & Lumbar curve (n = 103)
Mean SD Mean SD P-value* ESa Mean SD Mean SD Mean SD P-value*
EQ-5D-5L 0.93 0.11 0.91 0.12 0.402 0.19 EQ-5D-5L 0.92 0.13 0.93 0.11 0.95 0.10 0.271
SRS-22r SRS-22r
Function/activity 4.78 0.41 4.69 0.52 0.349 0.20 Function/activity 4.73 0.44 4.81 0.39 4.79 0.42 0.522
Pain 4.68 0.43 4.55 0.53 0.216 0.27 Pain 4.64 0.39 4.69 0.38 4.68 0.50 0.753
Appearance 3.96 0.63 3.72 0.76 0.116 0.34 Appearance 3.94 0.70 3.84 0.58 3.97 0.61 0.583
Mental Health 4.45 0.55 4.16 0.81 0.037 0.41 Mental Health 4.41 0.62 4.36 0.61 4.45 0.55 0.703
Satisfaction with management 1.09 1.84 0.90 1.47 0.662 0.11 Satisfaction with management 1.10 1.86 0.99 1.82 1.07 1.77 0.949
Total 4.46 0.40 4.25 0.57 0.032 0.42 Total 4.42 0.45 4.42 0.37 4.46 0.41 0.788

* P-value of independent t-test or analysis of variance test, where appropriate

aCohen’s effect size was calculated as the difference between mean scores, divided by pooled SD

N number of subjects, SD standard deviation, ES effect size