Table 5.
Association of 20-HETE and DiHETE levels with genotype distribution in patients
| 20-HETE (pmol/L) | DiHETE (nmol/l) | EET (nmol/l) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Carotid stenosis (n=90) |
Non-carotid stenosis (n=96) |
P* | carotid stenosis (n=90) |
Non-carotid stenosis (n=96) |
P* | Carotid stenosis (n=90) |
Non-carotid stenosis (n=96) |
P* | |
| rs17110453 | |||||||||
| AA | 1682 ± 186 | 1668 ± 180 | 83.13 ± 6.15 | 79.18 ± 7.14 | 63.80 ± 6.11 | 64.66 ± 5.53 | |||
| AC | 1656 ± 181 | 1698 ± 182 | 83.35 ± 10.72 | 81.68 ± 7.22 | 0.14 | 63.67 ±5 .14 | 63.11 ± 6.21 | ||
| CC | 1748 ± 193 | 1699 ± 191 | 0.55 | 83.12 ± 10.24 | 81.87 ± 6.13 | 58.72 ± 5.63 | 70.23 ± 6.55 | <0.01 | |
| rs751141 | |||||||||
| GG | 1702 ± 192 | 1679 ± 181 | 106.24 ± 11.22 | 78.24 ± 6.37 | <0.01 | 58.24 ± 4.67 | 73.28 ± 6.36 | <0.01 | |
| AG | 1623 ± 167 | 1612 ± 169 | 76.36 ± 6.15 | 74.16 ± 6.13 | 61.46 ± 6.58 | 62.42 ± 6.35 | |||
| AA | 1635 ± 184 | 1641 ± 176 | 0.42 | 71.88 ± 4.66 | 70.78 ± 5.22 | 63.68 ± 5.66 | 64.77 ± 6.44 | ||
| rs9333025 | |||||||||
| AA | 1602 ± 177 | 1567 ± 179 | 82.12 ± 8.51 | 79.36 ± 9.28 | 0.32 | 61.11 ± 5.67 | 62.68 ± 6.82 | ||
| AG | 1646 ± 161 | 1620 ± 171 | 85.89 ± 9.12 | 83.98 ± 8.76 | 61.89 ± 6.17 | 63.04 ± 6.35 | |||
| GG | 1833 ± 187 | 1635 ± 168 | <0.01 | 83.87 ± 8.02 | 81.88 ± 7.01 | 60.78 ± 5.66 | 61.92 ± 6.91 | 0.78 | |
Statistical significance was based on analysis of variance.
HETE, hydroxyeicosatetraenoic acid; EET, epoxyeicosatrienoic acids; DiHETE, dihydroxyeicosatrienoic acid.