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. 2014 Nov 26;1(1):e970883. doi: 10.4161/23262125.2014.970883

Figure 5.

Figure 5.

Ablation of Creb and Crem leads to reduced proliferation in the GE but not in the cortex of E13.5 embryos. (A–D) Representative micrographs of coronal telencephalic sections obtained from control (Ctr; A and B) and DM (C and D) embryos upon immunostaining with BrdU (A and C) and phospho-H3 (B and D) antibodies. (E) Quantitative analyses of the immunostaining with BrdU (Ea and Ec) and PH3 (Eb and Ec) antibodies in the GE (Ea and Eb) and in the cortex (Ec and Ed). Scale bar is 60 μm; N = 3–4. Asterisks indicate significant differences vs. control (Ctr) counterpart (Student's t-test) *P < 0 .05.