Figure 5.

Fusion of α_Dβ₂- and ICAM-1–deficient macrophages. A and C: Cells isolated from the peritoneum of α_Dβ₂^−/− (A) and ICAM^−/− (C) deficient mice 3 days after TG injection were plated on Permanox dishes, and IL-4–induced time-dependent fusion was determined. B and D: Representative images of WT, α_Dβ₂^−/−, and ICAM^−/− macrophages 24, 48, and 72 hours after the addition of IL-4. Data are expressed as means ± SD. n = 3 separate experiments (A and C). **P < 0.01. Scale bar = 100 μm. ICAM, intercellular adhesion molecule; TG, thioglycollate; WT, wild-type.