Figure 3.
In vitro pharmacologic activity of BMTP-11 on lung cancer cell lines. Cells were treated with serial molar concentrations of BMTP-11 or nontargeted D[KLAKLAK]2 peptide (control). A–F: Viability was assessed by WST-1 assay at 18 hours after treatments (right panels). Apoptosis was evaluated by Annexin V staining at 6 hours after treatments (left panels). Reverse sigmoidal curves in logarithmic scale for H460 (A), HOP62 (B), HOP92 (C), H226 (D), A549 (E), and H522 (F) treated with BMTP-11 or control. RFU, relative fluorescence unit.