Table 4.
Study | Observed no. with fever (O) | Observed prevalence | Summary prevalence from meta‐analysis model (8), ∗ | Summary sensitivity from meta‐analysis model (1), ∗ | Summary specificity from meta‐analysis model (1), ∗ | Option A Post‐test predictions obtained using summary sensitivity, summary specificity and summary prevalence (Equations (6) and (7)) | Option B Post‐test predictions obtained using summary sensitivity, summary specificity and observed prevalence (Equations (9) and (10)) | Option C Post‐test predictions obtained after bivariate meta‐regression of PPV and NPV on prevalence (Equations (12) and (13)) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Predicted PPV | Predicted NPV | Expected no. with fever ^ (E) | O/E | Predicted PPV | Predicted NPV | Expected no. with fever ^ (E) | O/E | Predicted PPV | Predicted NPV | Expected no. with fever ^(E) | O/E | ||||||
Brennan | 203 | 0.55 | 0.45 | 0.644 | 0.99 | 0.97 | 0.77 | 207.59 | 0.98 | 0.98 | 0.69 | 226.11 | 0.90 | 0.98 | 0.75 | 211.83 | 0.96 |
Davis | 18 | 0.27 | 0.48 | 0.661 | 0.98 | 0.97 | 0.76 | 24.41 | 0.74 | 0.94 | 0.89 | 16.85 | 1.07 | 0.96 | 0.78 | 22.71 | 0.79 |
Green | 9 | 0.43 | 0.46 | 0.631 | 0.98 | 0.97 | 0.76 | 10.92 | 0.82 | 0.97 | 0.78 | 10.58 | 0.85 | 0.96 | 0.76 | 10.80 | 0.83 |
Greenes | 109 | 0.36 | 0.46 | 0.67 | 0.98 | 0.97 | 0.77 | 110.91 | 0.98 | 0.96 | 0.83 | 94.12 | 1.16 | 0.95 | 0.78 | 106.11 | 1.03 |
Hoffman | 42 | 0.42 | 0.47 | 0.645 | 0.99 | 0.97 | 0.77 | 47.23 | 0.89 | 0.96 | 0.80 | 44.56 | 0.94 | 0.97 | 0.76 | 47.06 | 0.89 |
Hooker | 15 | 0.38 | 0.46 | 0.65 | 0.98 | 0.97 | 0.76 | 16.63 | 0.90 | 0.96 | 0.82 | 14.97 | 1.00 | 0.96 | 0.78 | 16.07 | 0.93 |
Lanham | 103 | 0.58 | 0.47 | 0.666 | 0.98 | 0.97 | 0.76 | 81.98 | 1.26 | 0.98 | 0.67 | 94.01 | 1.10 | 0.98 | 0.76 | 82.71 | 1.25 |
Muma | 87 | 0.39 | 0.46 | 0.662 | 0.98 | 0.97 | 0.78 | 84.73 | 1.03 | 0.96 | 0.83 | 75.98 | 1.15 | 0.95 | 0.78 | 84.66 | 1.03 |
Nypaver | 425 | 0.48 | 0.45 | 0.652 | 0.98 | 0.97 | 0.78 | 408.91 | 1.04 | 0.97 | 0.76 | 426.06 | 1.00 | 0.97 | 0.76 | 421.87 | 1.01 |
Rhoads | 27 | 0.42 | 0.47 | 0.683 | 0.98 | 0.96 | 0.77 | 20.25 | 1.33 | 0.96 | 0.80 | 18.12 | 1.49 | 0.96 | 0.77 | 19.78 | 1.36 |
Stewart | 59 | 0.75 | 0.43 | 0.65 | 0.98 | 0.97 | 0.78 | 59.88 | 0.99 | 0.99 | 0.49 | 67.79 | 0.87 | 0.98 | 0.56 | 65.61 | 0.90 |
Obtained from meta‐an the study in the row.
Expected number for the study in the row, based on using Equation (14) and the positive predictive value (PPV) and negative predictive value (NPV) in the prior two columns.