Skip to main content
. 2015 Mar 20;34(13):2081–2103. doi: 10.1002/sim.6471

Table 5.

Meta‐analysis results for overall calibration (O/E) when using model (16), as estimated in a frequentist or Bayesian framework.1

Example Predicted PPV and NPV obtained using… Statistical framework Summary O/E (95% CI) τ^ (95% CI) 95% prediction interval for O/E in a new population Probability 0.9 < O/E < 1.1 in a new population
Temperature data Option A Bayesian 1.02 (0.93 to 1.11) 0.10 (0.01 to 0.23) 0.78 to 1.31 0.67
Option A Frequentist 1.02 (0.95 to 1.10) 0.08 0.85 to 1.24
PTH data 1–2 h Option B Bayesian 1.02 (0.73 to 1.38) 0.14 (0.01 to 0.45) 0.56 to 1.74 0.40
Option B Frequentist 1.01 (0.79 to 1.29) 0 0.68 to 1.50
1

All frequentist analyses used method of moments to estimate the model.

All Bayesian analyses used a prior N(0, 1 000 000) for the mean ln(O/E) and a prior uniform(0, 0.25) for τ, with a 10 000 burn‐in followed by 100 000 samples for posterior inferences.

O/E, observed/expected; PPV, positive predictive value; NPV, negative predictive value.