Figure 5. Blocking PNAd Reduces Targeted Delivery of MP-MECA79 in a Transplant Mouse Model.
(A) FACS analysis of cell suspension from the inguinal DLNs of skin transplant recipients injected with either MP-Rhd-MECA79 or MP-Rhd, showing a greater accumulation of rhodamine-labeled MP-MECA79 compared with MPs.
(B) FACS analysis of cell suspension from the DLNs of skin transplant recipients injected with blocking anti-PNAd antibody 1 hr before injection of rhodamine-labeled particles.
(C) The absolute number of rhodamine-labeled particles in the four different groups of mice (n = 4 mice /group, *p < 0.05).