Fig 2. Time courses of ammonia, urea, alanine and L-glutamate output during L-glutamine infusion (5 mM) in livers from control and diabetic rats after a 24 hours fasting period.

L-Glutamine infusion was initiated at 10 minutes perfusion time, as indicated by the black arrows. Control, ●—●; type 1 diabetes, ■—■; type 2 diabetes, ○—○. Statistically significant differences between control and type 1 diabetes or control and type 2 diabetes are indicated by the symbols * and ‡, respectively.