Fig 2. Structures of initial hits.
The table includes their IC50 in the Gli-Luciferase assay in Ptch1-/- MEFs, and their Tanimoto coefficient (Tc) score compared to the closest known Smo ligand.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.