Table 5. Results from QPCR of the target genes in breast cancer patients treated with DOX-based chempotherapy who developed abnromal decline in LVEF after the completion of chemotherapy.
| Genes | Response differences ΔΔCt Units | 95% Lower confidence limit | 95% Upper confidence limit | P value | Fold change | Log2 fold change array data |
|---|---|---|---|---|---|---|
| ARG1 | 10.53 | 1.802 | 19.267 | 0.018 | 1483.1 | 3.6659 |
| CEACAM8 | 20.92 | 5.154 | 36.687 | 0.0093 | 1984332 | 4.4908 |
| DEFA4 | 16.312 | 6.135 | 26.489 | 0.0017 | 81350 | 4.0818 |
| DEFA3 | 8.263 | 3.915 | 12.61 | 0.0002 | 307.126 | 5.137 |
| ELANE | 20.309 | -3.113 | 43.73 | 0.0892 | 129871 | 3.762 |
| HP | 7.154 | -0.257 | 14.564 | 0.0585 | 142.382 | 3.5814 |
| MMP9 | 6.528 | -2.515 | 15.57 | 0.1571 | 92.27 | 4.3398 |
| OLFM4 | 37.053 | -10.556 | 84.662 | 0.1272 | 1.43E+11 | 3.5721 |