Table 3:
Cost to Ontario of CDI Antibiotic Treatment in 2014/2015 and Potential Total Yearly Cost of FMT
| Treatment Subgroups | Target Population | Estimated Total Cost, $ in Millions |
|---|---|---|
| Current standard treatment (antibiotics) in Ontario (HB + CB) | 5,810a | 47.8c |
| Standard treatment (antibiotics) for recurrent CDIs (HB + CB) in patients eligible for FMT | 1,575b | 13.9d |
| FMT treatment (HB + CB) for recurrent CDIs in eligible patients | 1,575 | 8.7e |
| Net budget impact of FMT for recurrent CDIs | –5.2f |
Abbreviations: CB, community based; CDI, Clostridium difficile infection; FMT, fecal microbiota therapy; HB, hospital based; RCDI, recurrent Clostridium difficile infection.
a
Total C. difficile infections (initial and recurrent) in 2014/2015: Health Analytics Branch, Ministry of Health and Long-Term Care.
b
Recurrent C. difficile infections (27.1% of 5,810).
c
[(CDITotal × 53%) × Cost CDIhb] + [(CDITotal × 47%) × Cost CDIcb] + [(RCDITotal × 53%) × Cost RCDIhb] + [(RCDIcb × 47%) × Cost RCDIcb].
d
[(RCDITotal × 53%) × Cost RCDIhb] + [(RCDIcb × 47%) × Cost RCDIcb].
e
[(RCDITotal × 53%) × Cost FMThb] + [(RCDIcb × 47%) × Cost FMTcb].
f
Difference between e and d.