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Cumulative incidence of venous thromboembolism (VTE) stratified by prophylaxis and no prophylaxis. The time to occurrence of VTE ranged from cycle 2 to cycle 10. The incidence of VTE increased over time with the increase in the number of cycles of asparaginase. The cumulative VTE incidence did not differ between the prophylaxis and the non-prophylaxis historical cohort by log-rank test (p = 0.8058).
