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. Author manuscript; available in PMC: 2016 Aug 4.
Published in final edited form as: Drug Metab Pharmacokinet. 2015 Jul 29;31(2):107–116. doi: 10.1016/j.dmpk.2015.07.002

Fig. 1.

Fig. 1

Plasma concentration–time profiles of efavirenz (EFV) and its metabolites after the administration of a single 600 mg single oral dose of EFV to healthy volunteers (n = 20) pretreatcd with placebo or 600 mg rifampin once daily for 10 days. (A) EFV; (B)) 8-hydioxyEFV (8-OHEFV); and (C) 8,14-dihydroxyEFV (8,14-diOHEFV). Each point represents mean ± SD.