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. Author manuscript; available in PMC: 2016 Aug 4.
Published in final edited form as: Drug Metab Pharmacokinet. 2015 Jul 29;31(2):107–116. doi: 10.1016/j.dmpk.2015.07.002

Fig. 4.

Fig. 4

Correlations analysis of the 3 h ratio of plasma concentrations of 8-hydroxyefavirenz (8-OHEFV) to that of (EFV) with; weight adjusted apparent oral clearance of EFV (A), AUC0–72 of EFV (B); AUC0–∞ of EFV (C); and the ratio of 8-OHEFV AUC0–72h to EFV AUC0–72h (D) after administration of a single 600 mg oral dose of EFV to healthy volunteers pretreatcd with placebo or 600 mg rifampin once daily for 10 days. Pearson's r is provided.