Table 1.

Somatic GNA14 and GNA11 Mutations Cause Vascular Tumors

Sample	Age (Years)	Sex	Site	Diagnosis	Somatic Mutation	No. of Reads in Tissue		No. of Reads in Blood		p Value
Ref.	Non-ref.	Ref.	Non-ref.
V101	0	male	neck	KHE	GNA14 c.614A>T (p.Gln205Leu)	81	8	96	0	2.4 × 10−3
V102	0	male	abdomen	TA	GNA14 c.614A>T (p.Gln205Leu)	NAa	NAa	NAa	NAa	NA
V103	2	male	cheek	LCH	GNA14 c.614A>T (p.Gln205Leu)	NAa	NAa	NAa	NAa	NA
V104	12	male	scalp	LCH	GNA11 c.547C>T (p.Arg183Cys)	55	16	NAb	NAb	NA
V105	2	male	cheek	LCH	GNA11 c.547C>T (p.Arg183Cys)	NAa	NAa	NAa	NAa	NA

Abbreviations are as follows: KHE, kaposiform hemangioendothelioma; LCH, lobular capillary hemangioma; NA, not applicable; non-ref., non-reference; ref., reference; and TA, tufted angioma.

^aMutation identified by Sanger sequencing.

^bExome sequencing performed on tumor only.