Table 3.
Semen Characteristics of Individual DCP813, in Whom the DNAJB13 p.Met278Arg Substitution Was Identified
| pH | Volume of Ejaculate (mL) | Total Sperm Count (106/Ejaculate) | Total Motility: PR + NP (%) | Progressive Motility: PR (%) | Vitality (%) | Morphology: Typical Forms (%) | |
|---|---|---|---|---|---|---|---|
| 2009 | 7.9 | 2.8 | 1.4 | 12 | 0 | 25 | 17 |
| 2010 | 7.9 | 3.5 | 0.07 | 0 | 0 | – | 5 |
| 2015 | 7.9 | 1.5 | 0.6 | 0 | 0 | 10 | NA |
| Lower reference limits (WHO, 2010)16 | 7.2 | 1.5 | 39 | 40 | 32 | 58 | 18 |
According to the World Health Organization (WHO) standards, sperm motility is categorized into three types: progressive motility (PR), which corresponds to rapid and slow progressive spermatozoa (formerly grades a and b, respectively); non-progressive motility (NP), which corresponds to static spermatozoa (i.e., motile but non-progressive spermatozoa; formerly grade c); and immotile spermatozoa, for which no beating and no progression is observed (formerly grade d). Spermatozoa with progressive motility were always absent in semen from individual DCP813 (normal value > 32%). Static motility was observed for 12% of spermatozoa only in 2009. The subsequent evaluations that were performed displayed no motile spermatozoa at all.