Figure 3.

The KIR Region Is >99.99% Covered by Sequence Data

(A) Target KIR region on chromosome 19: the gene locations are shown in orange, and pseudogenes are shown in gray. The KIR region varies in gene content, and shown are examples of two frequent A and B haplotypes. The KIR prefix is omitted from the gene names for clarity (see Appendix A). The human reference build hg19 (UCSC Genome Browser) has a KIR A haplotype. Underneath is a KIR B haplotype shown to scale.

(B) Read depth after stringent alignment of sequence reads (no base pairs mismatched, and duplicates were removed) from the PGF cell line to the PGF reference KIR haplotypes 1 (light purple) and 2 (dark purple).

(C) Coordinates and features of two short gaps in PGF KIR haplotype 2. The location of the gaps is shown on the right.