TABLE 3.
Multivariable model of factors related to subsequent surgery after partial mastectomy for DCIS
| Variable | Adjusted OR for subsequent surgery | 95 % CI | p value |
|---|---|---|---|
| Age (years) | <0.001 | ||
| 66–69 | Reference | ||
| 70–74 | 0.96 | 0.83–1.12 | |
| 75–79 | 0.91 | 0.78–1.06 | |
| 80–84 | 0.74 | 0.62–0.88 | |
| ≥85 | 0.57 | 0.44–0.73 | |
| Race | 0.305 | ||
| White | Reference | ||
| Non-White | 0.92 | 0.79–1.08 | |
| Patient residence | 0.030 | ||
| Metropolitan | Reference | ||
| Rural | 1.21 | 1.02–1.44 | |
| Charlson comorbidity index | 0.074 | ||
| 0 | Reference | ||
| 1 | 1.04 | 0.90–1.20 | |
| 2 | 0.81 | 0.67–0.98 | |
| ≥3 | 0.88 | 0.71–1.09 | |
| Overweight or obese | 1.09 | 0.94–1.27 | 0.236 |
| Tumor grade | <0.001 | ||
| Well-differentiated | Reference | ||
| Moderately differentiated | 1.06 | 0.89–1.26 | |
| Poorly differentiated | 1.36 | 1.13–1.63 | |
| Anaplastic | 1.02 | 0.82–1.26 | |
| NOS | 1.30 | 1.07–1.59 | |
| Tumor size (cm) | <0.001 | ||
| <2 | Reference | ||
| ≥ 2 | 2.27 | 1.98–2.59 | |
| Intraoperative pathologic assessment | 1.07 | 0.95–1.21 | 0.293 |
Abbreviations: DCIS ductal carcinoma in situ, OR odds ratio, CI confidence interval, NOS not otherwise specified