Fig. 1.
(A) A nephron scheme illustrating the expression of Kir4.1 in nephron segments circled by a red oval. (B) An image of isolated nephron segments which corresponds to the portion indicated by a red oval in Fig. 1A. The kir4.1 is expressed in the basolateral membrane from cortical thick ascending limb (cTAL) to the cortical collecting duct (CCD). (C) A scheme illustrating that NKCC2, NCC, ENaC and ROMK are expressed in the apical membrane of tubules from cTAL to CCD where Kir4.1 is expressed.