Table 2. Indepdenent predictors of sustained virologic response.

Virologic response parameters	Multivariate*		Multivariate†
	Hazard ratio (95% CI)	P value	Hazard ratio (95% CI)	P value
Age, yr	0.976 (0.923-1.032)	0.396	0.968 (0.917-1.023)	0.250
Cirrhosis, clinically diagnosed	0.085 (0.013-0.557)	0.010	0.084 (0.012-0.569)	0.011
Total bilirubin, mg/dL	0.323 (0.073-1.440)	0.138	0.331 (0.077-1.426)	0.138
Platelet count, 109/L	1.000 (1.000-1.000)	0.385	1.000 (1.000-1.000)	0.582
HCV RNA, log10IU/mL	0.968 (0.917-1.023)	0.026
HCV Ag, log10fmol/L			0.454 (0.226-0.914)	0.027

CI, confidence interval; HCV, hepatitis C virus; HCV Ag, HCV core antigen.

^*HCV RNA adjusted by age, cirrhosis, total bilirubin and platelet count; ^†HCV Ag adjusted by age, cirrhosis, total bilirubin and platelet count.