Table 3.
Association of rs77559927 with NOA risk
| SNP | Genotype | Controls (n = 493) | Patients (n = 342) | OR (95 % CI) | P corrected | P value | ||
|---|---|---|---|---|---|---|---|---|
| rs77559927 | N | % | N | % | ||||
| TT | 255 | 52.0 | 203 | 59.4 | 1.00 | |||
| TC | 208 | 42.0 | 121 | 35.4 | 0.73 (0.55–0.98) | 0.17 | 0.034 | |
| CC | 30 | 6.1 | 18 | 5.3 | 0.75 (0.41–1.39) | 1.00 | 0.366 | |
| Dominant model | TT vs. TC + CC | 0.73 (0.56–0.97) | 0.15 | 0.030 | ||||
| Recessive model | CC vs. TT + TC | 0.86 (0.47–1.56) | 1.00 | 0.616 | ||||
| P trend | 0.047 | |||||||
| P for HWE | 0.144 | |||||||
Italic values indicate significant findings (P < 0.05)
OR odds ratio, CI confidence interval, P trend P value for X 2 trend test, P corrected P value after correction