Table 5.
Time (days) | db/+ non-diabetic mice (grams) | db/db diabetic mice (grams) | ||
---|---|---|---|---|
CON | DOX | CON | DOX | |
Baseline | 27.1 ± 1.18 | 27.4 ± 0.39 | 45.3 ± 1.74* | 47.2 ± 1.49* |
Day 5 | 26.5 ± 1.02 | 23.9 ± 0.48** | 43.3 ± 1.81 | 43.1 ± 1.80** |
Day 7 | 25.4 ± 0.78 | 22.8 ± 1.39*** | 42.1 ± 1.36 | 39.6 ± 2.04*** |
Body weights were measured at the baseline and the 5 and 7-day experimental period in db/+ non-diabetic and db/db diabetic mice.
P < 0.001 compared to db/+ non-diabetic mice at the baseline;
P < 0.01 compared to the corresponding baseline (indicating the weight loss following DOX treatment on day-5);
P < 0.001 compared to the corresponding baseline (indicating the weight loss following DOX treatment on day-7).