Table 1.
Pathogen | Disease | Antigen | NDV Strain | Animal Model | Route of Inoculation * | Dose | Ref. |
---|---|---|---|---|---|---|---|
Influenza A H1N1 | Respiratory | HA | B1 | Mouse | iv, ip | 3 × 107 PFU; two doses | [13] |
HPAIV H5N1 | Respiratory | HA | LaSota | African green monkey | in | 2 × 107 PFU; two doses | [21] |
HPIV3 | Respiratory | HN | LaSota BC | African green and rhesus monkeys | in, it | 106.5 PFU; two doses | [17] |
EBOV | Hemorrhagic fever | GP | LaSota | Rhesus monkeys | in, it | Two doses | [19] |
SARS-CoV | Respiratory | S | LaSota | African green monkeys | in, it | Two doses | [20] |
SIV | simian AIDS | Gag | B1 | Mouse | iv, ip, in | 5 × 107 PFU; one or two doses | [27] |
HIV | AIDS | Gag | B1 | Mouse | in | 5 × 105 PFU; two doses | [14] |
HIV | AIDS | Env | LaSota | Guinea pig | in, im | 106 PFU; two or three doses | [28] |
HIV | AIDS | Env Gag | LaSota | Guinea pig | in | 106 PFU; two or three doses | [29] |
HIV | AIDS | Env (gp160, gp120) | LaSota | Guinea pig | in | 106 PFU; three doses | [30] |
HRSV | Respiratory | F | B1 | Mouse | in | 105.5 PFU; one dose | [31] |
NiV | Encephalitis | F/G | LaSota | Mouse Pig | im | 109 EID50; two doses | [32] |
Borrelia burgdorferi | Lyme | BmpA OspC | LaSota | Hamster | in, im, ip | 106 PFU | [33] |
NoV | Gastroenteritis | VP1 | LaSota BC | Mouse | in | 106 EID50; two doses | [25] |
* im: intramuscular, in: intranasal, ip: intraperitoneal, it: intratracheal, iv: intravenous, EID50: 50% embryo infective dose.