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Virulence in Drosophila (A) and mouse peritoneal (B) infection models. The wild type (WT) and the mutant (katA, p1m, p2m, and p1p2m) cells were prepared and the survival of infected animals was determined as described in Methods. The values are the averages from five replicate experiments for Drosophila (A) and three for mouse (B) infections. Statistical significance based on the log-rank test is indicated (**p < 0.005).
