Figure 1.
Steps for formation of peritoneal dissemination in gastric cancer. CDH1: Cadherin 1, E-cadherin; ANXA1: Annexin 1; NRAGE: Neurotrophin receptor-interacting melanoma antigen-encoding gene homolog; HIF1A: Hypoxia-inducible factor-1α subunit; PTEN: Phosphatase and tensin homolog; CXCR4: C-X-C motif chemokine receptor 4; CXCL12: C-X-C motif chemokine ligand 12; EGFR: Epidermal growth factor receptor; AREG: Amphiregulin; HBEGF: Heparin-binding EGF-like growth factor; MMP7: Matrix metalloproteinase 7; CTGF: Connective tissue growth factor; MELK: Maternal embryonic leucine zipper kinase; VEGFA: Vascular endothelial growth factor A; IRX1: Iroquois homeobox 1.