Table 2.
Influence of CGA7 complex on weight gain and metabolic variables in HFD- fed rats
| Parameter | Control | High fat diet | High fat diet + orlistat (30 mg/kg b.w.) | High fat diet + CGA7 (50 mg/kg b.w.) | High fat diet + CGA7 (100 mg/kg b.w.) | High fat diet + CGA7 (150 mg/kg b.w.) |
|---|---|---|---|---|---|---|
| Body weight gain (g) | 68.41 ± 1.18 | 112.0 ± 4.51# # # | 88.01 ± 3.68*** | 75.65 ± 3.44*** | 65.88 ± 2.14*** | 60.63 ± 2.89*** |
| Food intake (g/day) | 14.93 ± 0.77 | 8.26 ± 0.51# # # | 8.54 ± 0.40 | 7.78 ± 0.45 | 8.96 ± 0.45* | 6.98 ± 0.35 |
| Liver weight (g) | 3.87 ± 0.18 | 4.50 ± 0.19# | 3.47 ± 0.11*** | 3.56 ± 0.10*** | 3.57 ± 0.12*** | 3.39 ± 0.10*** |
| Mesenteric fat (g) | 0.59 ± 0.06 | 1.31 ± 0.12# # # | 0.98 ± 0.03* | 1.01 ± 0.07* | 1.0 ± 0.04* | 1.00 ± 0.07* |
| Epididymal fat (g) | 0.58 ± 0.02 | 2.07 ± 0.12# # # | 1.26 ± 0.05* | 1.06 ± 0.03*** | 0.84 ± 0.02*** | 0.74 ± 0.02** |
Data represent the means ± SEM (n = 6). Data were analysed using one way Anova for analysing the differences between groups (#, p < 0.05, # # #, p < 0.001) compared with control group. *, p < 0.05, **, p < 0.01 and ***, p < 0.001 compared with HFD group