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. 2016 Aug 5;15:135. doi: 10.1186/s12934-016-0533-4

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — HPLC-PDA analysis of a in vitro hydroxylation reaction mixture and b whole cells bioconversion of naringenin. (i) control reaction of naringenin using E. coli BL21 (DE3); (ii) hydroxylation of naringenin with CYP450 BM3, (iii) M13 and (iv) M15, respectively