Table 2.
Anti-inflammatory activity of Monotheca buxifolia hydro-ethanolic extract (MBHE) in carrageenan induced paw edema in mice
| Treatment | 1st h | 2nd h | 3rd h | 4th h | 5th h |
|---|---|---|---|---|---|
| Group 1 Saline |
0.235 ± 0.012 | 0.227 ± 0.026 | 0.240 ± 0.011 | 0.210 ± 0.016 | 0.230 ± 0.036 |
| Group 2 Carrageenan |
0.340 ± 0.016### | 0.370 ± 0.028### | 0.395 ± 0.025### | 0.490 ± 0.057### | 0.440 ± 0.028### |
| Group 3 Aspirin (150 mg/kg) |
0.255 ± 0.028** | 0.250 ± 0.035*** | 0.252 ± 0.020*** | 0.325 ± 0.052*** | 0.305 ± 0.019*** |
| Group 4 (MBHE 50 mg/kg) |
0.262 ± 0.022** | 0.282 ± 0.012** | 0.287 ± 0.025*** | 0.292 ± 0.015*** | 0.352 ± 0.029** |
| Group 5 (MBHE 100 mg/kg) |
0.227 ± 0.040*** | 0.277 ± 0.035** | 0.290 ± 0.046*** | 0.287 ± 0.037*** | 0.347 ± 0.029** |
| Group 6 (MBHE 150 mg/kg) |
0.210 ± 0.028*** | 0.257 ± 0.026*** | 0.287 ± 0.022*** | 0.272 ± 0.044*** | 0.330 ± 0.038** |
Values are expressed as mean paw volume in ml ± SD. ANOVA followed by Tukey’s post hoc test. ### P < 0.001 compared to group 1. **P < 0.01, ***P < 0.001 compared to group 2. n = 6 animals per group