Table 3.
TLR2 SNP Genotypes and Minor Allele Frequencies (MAF) along with Hardy Weinberg Equilibrium Values in Asthmatic and Control Groups
| SNP Genotypes | Asthmatics N (%) | Controls N (%) | Total N (%) | Hardy Weinberg Equilibrium (X 2, p > 0.05) |
|---|---|---|---|---|
| TLR2 +596 | 0.14 | |||
| CC | 7 (11.3) | 17 (27.9) | 24 (19.5) | |
| CT | 36 (58.1) | 27 (44.3) | 63 (51.2) | |
| TT | 19 (30.6) | 17 (27.8) | 36 (29.3) | |
| MAF (C) | 0.35 (35) | 0.36 (36) | ||
| TLR2 -16934 | 0.65 | |||
| TT | 17 (27.4) | 14 (23.0) | 31 (25.2) | |
| AT | 32 (51.6) | 26 (42.6) | 58 (47.2) | |
| AA | 13 (21.0) | 21 (34 .4) | 34 (27.6) | |
| MAF (A) | 0.35 (35) | 0.38 (38) | ||
| TLR2 +399 | 0.88 | |||
| AA | 23 (37.1) | 29 (47.5) | 52 (42.3) | |
| AG | 33 (53.2) | 26 (42.6) | 59 (48.0) | |
| GG | 6 (9.7) | 6 (9.8) | 12 (9.7) | |
| MAF (G) | 0.32 (32) | 0.26 (26) | ||
| TLR2 +1349 | 2.53 | |||
| TT | 56 (90.3) | 57 (93.4) | 113 (91.9) | |
| CT | 6 (9.7) | 3 (4.9) | 9 (7.3) | |
| CC | 0 | 1 (1.6) | 1 (0.8) | |
| MAF (C) | 0.05 (5) | 0.03 (3) |
Hardy Weinberg equilibrium chi-square values were acquired under a p-value >0.05