Table 2.

Correlations between clinical parameters and the three ALK rearrangement detection methods in all three cohorts

	FISH		Ventana IHC		Dako IHC
Variable	Correlation	P-value	Correlation	P-value	Correlation	P-value
Gender	0.020	0.601	0.043	0.230	0.078	0.028
Age	−0.002	0.959	−0.049	0.167	−0.057	0.108
Stage	0.047	0.197	0.035	0.326	0.042	0.238
Smoking	−0.188	<0.001	−0.140	<0.001	−0.166	<0.001

FISH positive vs negative, Ventana IHC Assay intensity 3 vs the other intensities, Dako IHC Assay score <8 vs. ≥8, Age at diagnosis ≤70 years vs. >70 years, Stage IA + IB vs. II-IV, Smoking smokers + ex-smokers vs. never smokers