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. 2016 Aug 5;16:606. doi: 10.1186/s12885-016-2652-z

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Flow diagram of the study design. A total of 815 Human Epidermal Growth Factor Receptor 2 (HER2) negative patients who received neoadjuvant chemotherapy with the regimen of cyclophosphamide, epirubicin and 5-fluorouracil; cyclophosphamide, epirubicin and 5-fluorouracil followed by paclitaxel or docetaxel and epirubicin; navelbine and epirubicin; or paclitaxel and carboplatin or paclitaxel and cisplatin were included in this study