Table 1.
Demographic Characteristics of the Study Cohorts
| Samplea | Age, Mean (SD), y | Female Sex, No./Total No. | DSM-IV CAD Criterion Count, Mean (SD) | CAD Diagnosis, No./Total No. of Participants | Correlation With DSM-IV CAD Criterion Count, r2 | |||
|---|---|---|---|---|---|---|---|---|
| AD | CD | ND | OD | |||||
| Yale-Penn African American | 41.3 (9.7) | 2209/4750 | 1.7 (2.2) | 1296/4750 | 0.40 | 0.30 | 0.36 | 0.15 |
| Yale-Penn European American | 38.6 (11.5) | 1712/4221 | 2.0 (2.3) | 1388/4221 | 0.27 | 0.32 | 0.31 | 0.23 |
| SAGE African American | 39.9 (7.3) | 638/1250 | 1.4 (2.2) | 276/1250 | 0.43 | 0.43 | 0.39 | 0.17 |
| SAGE European American | 38.4 (9.7) | 1478/2640 | 1.0 (1.9) | 434/2640 | 0.51 | 0.61 | 0.40 | 0.41 |
| ICGHD | 36.2 (9.1) | 838/1893 | 3.2 (2.5) | 1062/1893 | 0.24 | 0.24 | 0.25 | 0.33 |
Abbreviations: AD, alcohol dependence; CAD, cannabis dependence; CD, cocaine dependence; ICGHD, International Consortium on the Genetics of Heroin Dependence; ND, nicotine dependence; OD, opioid dependence; SAGE, Study of Addiction: Genetics and Environment.
a
Samples are described in the Participants and Diagnostic Procedure subsection of the Methods section.