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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: JAMA Psychiatry. 2016 May 1;73(5):472–480. doi: 10.1001/jamapsychiatry.2016.0036

Table 2.

SNPs Associated With DSM-IV CAD at P < 1.0 × 10−5 in the Discovery Meta-analysis Trimmed for SNPs in Linkage Disequilibrium

Chromosome Base Pair
Positiona 		Effect
Allele		 Reference
Allele		 SNP Gene Effect Allele
Frequency
P Value for Meta-analysis
African
American
Cohort		 European
American
Cohort		 African
American
Cohort		 European
American
Cohort		 All Participants
1 88729683 C T rs74823926 NA 0.96 0.97 5.26 × 10−7 6.36 × 10−1 1.40 × 10−5
2 39166173 T G rs114383460 ARHGEF33 0.96 NA 1.09 × 10−6 NA NA
2 78028838 T A rs12621150 NA 0.85 0.90 7.67 × 10−1 1.05 × 10−6 2.91 × 10−4
2 100451676 T C rs7586604 AFF3 0.39 0.16 4.15 × 10−5 6.19 × 10−3 1.06 × 10−6
2 103764414 G A rs144605126 NA 0.96 NA 8.67 × 10−7 NA NA
2 118490901 G A rs150064803 NA 0.95 NA 3.41 × 10−7 NA NA
2 167214714 G A rs143020225 SCN9A 0.95 NA 7.19 × 10−7 NA NA
3 149013935 G A rs143244591b RP11-206M11.7 0.96 NA 2.18 × 10−8b NA NA
4 25201318 A T rs73252553 PI4K2B 0.96 0.90 1.18 × 10−3 2.28 × 10−5 1.66 × 10−7
4 119716950 A C rs28595532 SEC24D 0.92 0.94 2.02 × 10−7 1.08E-01 1.13 × 10−6
5 11892384 T C rs114311699 CTNND2 0.96 NA 3.78 × 10−7 NA NA
5 177746600 G C rs10066744 COL23A1 0.96 NA 4.82 × 10−7 NA NA
6 51221457 A G rs17665889 NA 0.94 0.90 1.51 × 10−1 9.41 × 10−8 2.58 × 10−4
7 84952631 A G rs12534830 NA 0.88 0.66 7.76 × 10−3 1.54 × 10−5 4.52 × 10−7
8 3073489 A G rs77378271b CSMD1 0.96 0.94 2.13 × 10−1 2.76 × 10−8b 4.60 × 10−8b
9 29364327 G T rs10969106 NA NA 0.97 NA 7.39 × 10−8 NA
10 31981385 T C rs115553536 NA 0.94 NA 6.46 × 10−7 NA NA
10 43592809 G C rs74400468 RET 0.96 0.97 5.53 × 10−2 1.59 × 10−6 6.46 × 10−7
10 70490106 A T rs12218439 CCAR1 0.96 0.96 1.01 × 10−6 2.01 × 10−1 1.13 × 10−4
10 95659958 A G rs146091982 SLC35G1 0.95 NA 1.95 × 10−7 NA NA
11 20561010 C G rs73443003 NA 0.75 NA 1.31 × 10−6 NA NA
11 81433204 A AAAG rs200453611 NA 0.91 0.84 9.43 × 10−7 6.24 × 10−1 6.81 × 10−4
11 108899423 GTA G rs200391037 NA 0.96 0.88 1.02 × 10−1 3.72 × 10−6 1.32 × 10−6
12 56274155 T C rs193047854 NA 0.97 NA 7.06 × 10−7 NA NA
20 21706604 A AT rs199783889 NA 0.94 NA 3.32 × 10−7 NA NA
21 18019319 T C rs78068107 NA 0.96 NA 1.02 × 10−6 NA NA
21 48006053 A C rs186825689b NA 0.96 NA 1.86 × 10−8b NA NA
a

Indicates in human genome assembly build 37.

b

Indicates genome-wide significant SNPs and P values.