Fig. (10).

Histological findings in furcation defect at 4 weeks for collagen hydrogel scaffold loaded with FGF2. (A) A large amount of regenerated bone was observed in the defect. (B) Higher magnification image of the framed area (1) in (A). Periodontal ligament-like tissue showed a fiber-rich layer. (C) Higher magnification image of the framed area (2) in (A). Cementum-like tissue, resembling acellular cementum, was detected on the root surface. CT, connective tissue; PB, preexisting bone; NB, new bone; NC, new cementum-like tissue; PL, periodontal ligament-like tissue; R, root; arrowheads, apical notches. Staining: hematoxylin and eosin (A, C) and Masson’s trichrome (B). (Scale bars represent 1 mm (A) and 100 µm (B, C)).