Table 2. Breast Cancer and SSc: Proposed Risk Factors.

Prolonged use of CCBs (> 10 years)	Li et al [37, 39] Fitzpatrick et al [38] Daling [40]
Increased collagen deposition	Martin and Boyd [42]
Hormonal influence (increased prolactin and DHEA)	Artlett et al [43]
CAV1 regulated TGF/Smad pathway	Qian and Ueno [44]