| 1. Was the spectrum of patients representative of the patients who will receive the test in practice? |
44 |
15 |
41 |
| 2. Were selection criteria clearly described? |
82 |
1 |
17 |
| 3. Is the reference standard likely to correctly classify the target condition? |
93 |
4 |
3 |
| 4. Is the time period between reference standard and index test short enough to be reasonably sure that the target condition did not change between the two tests? |
93 |
0 |
7 |
| 5. Did the whole sample or a random selection of the sample, receive verification using a reference standard of diagnosis? |
73 |
3 |
24 |
| 6. Did patients receive the same reference standard regardless of the index test result? |
99 |
0 |
1 |
| 7. Was the reference standard independent of the index test (i.e. the index test did 1t form part of the reference standard)? |
99 |
0 |
1 |
| 8. Was the execution of the index test described in sufficient detail to permit replication of the test? |
97 |
1 |
2 |
| 9. Was the execution of the reference standard described in sufficient detail to permit its replication? |
95 |
2 |
3 |
| 10. Were the index test results interpreted without knowledge of the results of the reference standard? |
82 |
3 |
15 |
| 11. Were the reference standard results interpreted without knowledge of the results of the index test? |
22 |
6 |
72 |
| 12. Were the same clinical data available when test results were interpreted as would be available when the test is used in practice? |
26 |
2 |
72 |
| 13. Were un-interpretable/ intermediate test results reported? |
69 |
9 |
22 |
| 14. Were withdrawals from the study explained? |
42 |
21 |
37 |
