Table 2.
Partial Pearson correlations of natural log–transformed urinary biomarkers indexed to urinary creatinine with each other and participant characteristics
| Biomarker | Age, yr | MAP, mmHg | Baseline eGFR, ml/min per 1.73 m2 | UACR, mg/mg | HbA1C, % | BMI, kg/m2 | MCP-1-to-Cr, pg/mg | KIM-1-to-Cr, pg/mg | IL-18-to-Cr, pg/mg | YKL-40-to-Cr, pg/mg |
|---|---|---|---|---|---|---|---|---|---|---|
| MCP-1-to-Cr, pg/mg | −0.001 | 0.14a | 0.05 | 0.26a | 0.11b | 0.06 | 0.50b | 0.25b | 0.20b | |
| KIM-1-to-Cr, pg/mg | 0.03 | 0.01 | −0.004 | 0.21b | 0.05 | 0.07 | 0.50b | 0.24b | 0.16b | |
| IL-18-to-Cr, pg/mg | −0.05 | 0.11b | 0.09 | 0.19 | 0.23a | 0.16a | 0.25b | 0.24b | 0.29b | |
| YKL-40-to-Cr, pg/mg | −0.02 | 0.13b | 0.09 | 0.02 | 0.14a | 0.02 | 0.20b | 0.16b | 0.29b |
MAP, mean arterial pressure; UACR, urinary albumin-to-creatinine ratio; HbA1C, hemoglobin A1C; BMI, body mass index; MCP-1, monocyte chemotactic protein-1; Cr, creatinine; KIM-1, kidney injury molecule-1.
P<0.01.
P<0.05.