Figure 3.

Adjusted percentage of participants by APOL1 risk status and eGFR trajectory category. Adjusted percentage total 100% across all eight combinations of APOL1 risk status and eGFR trajectory category. Overall, 22% of the participants had the APOL1 high–risk genotype, and 78% had the APOL1 low–risk genotype. The adjusted percentages were estimated from multinomial regression using the four eGFR trajectory patterns as outcomes. Covariates included age at randomization, sex, randomized drug treatment group, randomized BP target, baseline eGFR, log(proteinuria), diastolic BP, and follow-up time for trajectory estimate.