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Berberine attenuates aminoglycoside resistance of A. xylosoxidans and B. cepacia.
| Strains | MIC (μg/ml) with (+) and without (–) addition of 256 μg/ml BB | |||||||
|---|---|---|---|---|---|---|---|---|
| AMK | ABK | GEN | TOB | |||||
| – | + | – | + | – | + | – | + | |
|
A. xylosoxidans PAGU 0002T |
>512 | 64 | >512 | 64 | >512 | 16 | 512 | 16 |
|
B. cepacia PAGU 0013T |
256 | 16 | 128 | 16 | 256 | 16 | 256 | 8 |
|
A. baumannii PAGU 1567T |
32 | 32 | 32 | 32 | 64 | 64 | 8 | 8 |
AMK, amikacin; ABK, arbekacin; BB, berberine; GEN, gentamicin; TOB, tobramycin.
