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. 2016 Jun 9;16(8):983–997. doi: 10.1080/14737175.2016.1194756

Table 4.

Case reports and series of thalamic and subthlamic deep brain stimulation (DBS) in patients with posttraumatic tremor.

Author Target Outcome Follow-up
Broggi et al. (1993) [96] Unilateral VIM DBS Improved function without tremor 10 months
Hooper et al. (2001) [97] Unilateral junction of ZI and subthalamic region DBS Long term abolition of the movement disorder after lesioning effect 44 months
Umemura et al. (2004) [98] Unilateral VIM DBS 52% increase in functional speed in timed task performance trials, and increased independence in activities of daily living 12 months
Green et al. (2005) DBS of right ZI and VOP (ipsilateral) Increased functional use of left arm 2 years
Broggi et al. (2006) [99] Three patients treated with ZI and VOA/VOP DBS Marked benefit with all patients regained autonomous self-feeding 12–36 months
Foote et al. (2006) [2] Three patients treated with ipsilateral, dual VIM, and VOA/VOP lead DBS 38–67% reduction in TRS scores 12 months, 6 months, and 8 months, respectively
Franzini et al. (2011) [100] Nine patients; six unilateral, three bilateral VIM DBS >50% tremor reduction in all cases 12 months
Issar et al. (2013) [38] Three patients managed with unilateral VIM, one patient with bilateral VIM and One patient with bilateral Gpi Percentage change in TRS scores was available for three patients and ranged from 14.3% to 56.5% Mean follow-up 2 years
Reese et al. (2011) [101] Unilateral VIM + STN Reduction in UPDRS III score and TRS score from 25 and 8 to 8 and zero, respectively 5 years
Follett et al. (2014) [39] Bilateral VIM Tremor reduction from a score of 3 to a score of 1 in the right arm and from 3.5 to 0 in the left arm (TETRAS scale) 18 months

GPi, globus pallidus internus; STN, subthalamic nucleus; TETRAS, The Essential Tremor Rating Assessment Scale; TRS, tremor rating scale; VIM, ventral intermedius nucleus; Voa, ventralis oralis anterior nucleus; Vop, ventralis oralis posterior nucleus; Zi, zona incerta.