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. 2016 Aug 1;9:4773–4783. doi: 10.2147/OTT.S103940

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© 2016 Chen et al. This work is published and licensed by Dove Medical Press Limited

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Armillarikin-induced loss of mitochondrial integrity in human hepatocellular carcinoma cells.

Notes: After DMSO, or 12.5 or 25 µM armillarikin treatment for 3 days, (A) HepG2 and (B) HA22T cells were stained with DiOC6(3). MTP of cells was analyzed using flow cytometry (right panel). Percentage of cells with low MTP is expressed as mean ± SD. ***P<0.001 (Student’s t-test) compared with DMSO control.

Abbreviations: DMSO, dimethyl sulfoxide; DiOC6(3), dihexyloxacarbocyanine iodide; HCC, hepatocellular carcinoma; MTP, Mitochondrial transmembrane potential; SD, standard deviation.