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. 2016 Aug 5;11(8):e0160355. doi: 10.1371/journal.pone.0160355

Fig 4. Expression of FosB proteins in HPC and PFC of human cocaine addiction and depression patients.

Fig 4

(A) Western blot of FosB proteins from the HPC and PFC of human cocaine addicts (Coc) and controls (Con). (B) Quantitation reveals a cocaine-dependent decrease in many FosB proteins in the HPC but not PFC (*:p<0.05, #:p = 0.05). (C) Western blot of FosB proteins from the HPC and PFC of human depression patients off (Dep) or on antidepressants (Dep + AD) and controls (Con). (D) Quantitation reveals a depression-dependent decrease in some FosB proteins in the HPC but not PFC (*:p<0.05). Error bars indicate mean +/- SEM.