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. 2016 Aug 5;11(8):e0159640. doi: 10.1371/journal.pone.0159640

Fig 8. Estradiol affected Henkel 100-induced responses in the OE.

Fig 8

(A) Representative submerged EOG responses to Henkel 100 (1:5,000) were recorded from the surface of the septum of female mice. The amplitude was lowered after preincubation with 1 μM estradiol and recovered after washout. (B) The graph shows the relative response amplitudes to Henkel 100, Henkel 100 after estradiol preincubation and after estradiol washout. The response was significantly decreased after estradiol preincubation (39.4 ± 8.3%) and then recovered to 82.0 ± 9.5% after washout (n = 4). (C) Representative submerged EOG responses to Henkel 100 (1:5,000) were recorded under control conditions, after a 4-min preincubation with 1 nM estradiol and after washout. The amplitude value was reduced after preincubation with 1 nM estradiol and recovered after washout. (D) The graph shows the relative response to Henkel 100, Henkel 100 after estradiol preincubation and after estradiol washout. The response was significantly decreased after estradiol preincubation (42.2 ± 3.8%) and recovered to 72.2 ± 2.2% of the starting value after washout (n = 3). Significant data are labeled: *p ≤ 0.05, **p ≤ 0.01.